Volume 89 Issue 36 | p. 54 | Concentrates
Issue Date: September 5, 2011

Nitric Oxide-Emitting Nanomaterials Kill Microbes

Department: Science & Technology
News Channels: Biological SCENE, Materials SCENE
Keywords: bactericidal nanoparticles, antibiotic resistance, nitric oxide

Nanomaterials modified to release nitric oxide, a compound produced by inflammatory cells to kill invading microbes, might be future therapeutics for fighting antibiotic-resistant pathogens, according to a research team led by Mark H. Schoenfisch of the University of North Carolina, Chapel Hill. Building on previous work showing that NO-releasing nanoparticles kill bacteria more efficiently than small-molecule NO donors (ACS Nano, DOI: 10.1021/nn700191f), grad student Yuan Lu and postdoc Bin Sun reported that NO-releasing . . .

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