Volume 89 Issue 42 | p. 54 | Concentrates
Issue Date: October 17, 2011

Peptide Patrols The Gut

Antimicrobial molecule maintains a bacteria-free zone on intestinal surfaces
Department: Science & Technology
News Channels: Biological SCENE
Keywords: microbiome, immunology, antimicrobial peptide

An antimicrobial peptide released by cells lining the intestines is responsible for policing the bacteria that reside there, according to a team led by immunologist Lora V. Hooper of the University of Texas Southwestern Medical Center (Science, DOI: 10.1126/science.1209791). Biologists have known that there is an approximately 50-µm-thick, mucus-filled “demilitarized zone” protecting the gut from bacterial attack, Hooper says. . . .

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