Issue Date: December 19, 2011
Closing The Loop
Cyanobacteria have a complete tricarboxylic acid (TCA) cycle after all, Donald A. Bryant and Shuyi Zhang of Pennsylvania State University report (Science, DOI: 10.1126/science.1210858). Their finding corrects a decades-old misconception and could lead to improved models for engineering microbes for biotechnology applications.
The TCA cycle—also known as the citric acid cycle or the Krebs cycle—is one of the central pathways in cellular metabolism. It . . .
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