Volume 89 Issue 8 | pp. 33-34 | Concentrates
Issue Date: February 21, 2011

Epigenetic Clues To Arsenic Toxicity

Newly identified tumor-suppressor genes could help unravel how long-term arsenic exposure leads to diseases
Department: Science & Technology
News Channels: Environmental SCENE
Keywords: arsenic, epigenetics, DNA methylation, toxicity

Long-term exposure to low levels of arsenic in drinking water—a public health problem affecting tens of millions of people globally—is associated with an increased incidence of heart disease, diabetes, and cancer. Studies on arsenic poisoning have identified epigenetic changes such as altered DNA methylation as a probable cause of these health effects, but it’s still unclear whether multiple genes and pathways are affected. Toxicologists led by Rebecca C. Fry of the University of . . .

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