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Web Date: February 2, 2011

Capillary Electrophoresis Goes Western

Protein Separation: A new method demands less time and sample than does conventional Western blotting
Department: Science & Technology, Government & Policy
News Channels: Environmental SCENE
Keywords: Capillary electrophoresis, Western blot, protein separation

Biochemists may soon have more time on their hands. Researchers in Michigan have speeded up Western blotting, a biochemistry workhorse for protein separations, by coupling it to an analytical chemistry mainstay, capillary electrophoresis (CE) (Anal. Chem., DOI 10.1021/ac102671n). The new technique produces data in a quarter of the time, and with a fraction of the sample, that Western blots normally use.

Western blotting detects a specific protein in a mixture. . . .

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