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Web Date: August 18, 2011

Probing Enantiomer Purity

Stereochemical Analysis: New method quickly reveals the composition of mixtures of enantiomers of carboxylic acids
Department: Science & Technology
Keywords: enantiomer, hirality, enantiomeric excess, exciton-coupled circular dichroism

Molecules that are mirror images of each other can produce vastly different biological effects. For instance, one enantiomer of a drug may alleviate symptoms, while its mirror image lacks activity or even causes side effects. Therefore, synthetic chemists develop methods to selectively synthesize just one enantiomer. Now they can assess the fruits of their labor more easily with a technique that quickly quantifies the relative amount of each mirror image in a mixture of enantiomers . . .

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Chemical & Engineering News
ISSN 0009-2347
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