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Web Date: September 26, 2011

Corralling Llama Antibodies For Small Molecules

Antibody Production: New technique isolates unusually stable antibodies against a potential endocrine disrupter
Department: ACS News
News Channels: Analytical SCENE
Keywords: single-domain antibodies, triclocarban, endocrine disrupter, llama

Along with a nasty reputation for being spitters, llamas have another unusual feature: They produce a type of antibody that lacks a light chain. Scientists think that these simple antibodies could be useful tools in the lab and clinic because they’re easier to produce and more resistant to heat than conventional antibodies. But so far, these so-called single-domain antibodies have proven useful for detecting only large molecules like proteins. Now, for the first time, researchers . . .

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