Volume 90 Issue 16 | p. 20
Issue Date: April 16, 2012

Cover Stories: Controlling The Code

Probing Questions

A public-private partnership aims to find and share new compounds for epigenetics research
Department: Business
Keywords: drug discovery, epigenetics, pharmaceuticals, industry-academia collaboration

Epigenetics, the study of how gene expression is controlled without changes to underlying DNA, holds great promise as a new avenue for drug discovery. But the field has been stalled by the lack of good tool compounds—highly selective chemical probes that help researchers determine the biological function of a given target.

The Structural Genomics Consortium, a public-private partnership set up in 2004 and dedicated to open-access drug . . .

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