Volume 90 Issue 22 | p. 47 | Concentrates
Issue Date: May 28, 2012

Easy Mass Measurement Of Viruses And Nanoparticles

Technique enables analysis of previously hard-to-measure particles
Department: Science & Technology | Collection: Life Sciences
News Channels: Analytical SCENE, Nano SCENE, Materials SCENE, Biological SCENE
Keywords: virus, nanoparticles, mass spectrometry, laser-induced acoustic desorption spectroscopy

A fast, simple way to find the mass of viruses and nanoparticles has been developed by researchers in Taiwan (Anal. Chem., DOI: 10.1021/ac300615v). The mass distributions of viruses and nanoparticles—which range between 1 megadalton and 1 gigadalton—are hard to measure. Most viruses and nanoparticles have 50 charges or fewer when ionized. This range lies in a detection black hole: Mass spectrometry can easily cope with small molecules . . .

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