Volume 90 Issue 49 | p. 33 | Concentrates
Issue Date: December 3, 2012

Worm Defends Itself By Chemical Detox

The roundworm C. elegans protects itself by glycosylating bacterial toxins it encounters
Department: Science & Technology
News Channels: Biological SCENE
Keywords: chemical ecology, C. elegans, toxins, glycosylation

The roundworm Caenorhabditis elegans survives assaults from pathogenic microbes by chemically modifying small-molecule toxins, a multi-institution research team has found (ACS Chem. Biol., DOI: 10.1021/cb300520u). Frank C. Schroeder of Cornell University, Arthur S. Edison of the University of Florida, and coworkers examined how C. elegans defends itself against two unrelated bacterial toxins, 1-hydroxyphenazine released by Pseudomonas aeruginosa and . . .

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