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Web Date: January 2, 2012

Method Cleans Up Cluttered Spectra

Biological NMR: A new way to remove unwanted signals could make analyzing complex biological samples easier
Department: Science & Technology
News Channels: Analytical SCENE, Biological SCENE
Keywords: signal suppression, background subtraction, NMR, metabolomics, metabolite profiling, glucose, mixture analysis

When researchers use nuclear magnetic resonance to analyze the contents of biological samples, signals from a few compounds often swamp out the rest. A new method suppresses the unwanted signals by first boosting them (Anal. Chem., DOI: 10.1021/ac202548n). Its developers say that the method could help researchers analyze low-abundance compounds in patient samples and discover small-molecule biomarkers for disease.

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Chemical & Engineering News
ISSN 0009-2347
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