• CORRECTION: This story was updated on May 24, 2012. The research team estimated solvation energies for 56,000 sequences coding for tRNA, not 5,600, as originally stated.

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Web Date: May 24, 2012

DNA’s Destiny Lies In Its Solvation

Genomics: Researchers can predict whether a DNA sequence codes for mRNA or tRNA based on its interactions with water
Department: Science & Technology | Collection: Life Sciences
News Channels: Biological SCENE, JACS In C&EN
Keywords: DNA, solvation energy, genomics, mRNA, tRNA

As scientists sequence more and more genomes, they need efficient tools to parse the mountains of data. For example, to uncover the genetic causes of disease, scientists often need to determine whether a DNA sequence codes for a protein. Using basic solvation properties of DNA, researchers have now developed a simple and accurate method for predicting whether a stretch of DNA codes for messenger RNA (mRNA), which translates into a . . .

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