Volume 91 Issue 28 | p. 24 | Concentrates
Issue Date: July 15, 2013

Aldols On The Cheap

New version of the aldol reaction makes chiral alcohols inexpensively
Department: Science & Technology
News Channels: Organic SCENE
Keywords: organic chemistry, asymmetric synthesis, aldol, chiral auxiliary

To form carbon-carbon bonds with stereochemical control, chemists often turn to the aldol reaction, which forms chiral alcohols from two carbonyl compounds. Researchers have many options for this transformation, but new work suggests they could save money on it (Angew. Chem. Int. Ed. 2013, DOI: 10.1002/anie.201302535). William R. Roush of Scripps Research Institute Florida, who . . .

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