Volume 91 Issue 35 | pp. 17-24
Issue Date: September 2, 2013

Cover Story

Nature’s Second Act

By tapping directly into the microbial genome for clues to novel drug candidates, researchers hope to revive interest in natural products
Department: Business
News Channels: Biological SCENE
Keywords: drug discovery, genome mining, natural products, pharmaceuticals, biotech

As you walk barefoot through your backyard on a hot summer day, luxuriating in the grass between your toes, stop to contemplate the silent war going on below you. Tens of thousands of microorganisms are sharing that little patch of earth, chattering with one another through complex chemical signals, battling for food, and picking one another off using molecular weapons.

The molecules that microbes make to give themselves a competitive edge are the basis of . . .

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