Volume 91 Issue 50 | p. 8 | News of The Week
Issue Date: December 16, 2013 | Web Date: December 12, 2013

Nanobiopsy Technique Samples A Cell Without Killing It

Analytics: Computer-controlled nanopipette nondestructively extracts samples from living cells
Department: Science & Technology
News Channels: Analytical SCENE, Biological SCENE, Nano SCENE
Keywords: nanopipette, nanobiopsy, scanning ion conductance microscopy, SICM, electrowetting

When scientists investigate the inner contents of a cell, the methods they use often end up killing it. Now, bioengineers have introduced a kind of cellular biopsy—a system to extract femto­liters of material from a cell without destroying it (ACS Nano 2013, DOI: 10.1021/nn405097u). The technique permits repeat sampling of a living cell, enabling study of its dynamic biochemistry over time.

Current methods that use . . .

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