Hydrogel Drug Depots Refilled On The Fly | Chemical & Engineering News
Volume 92 Issue 34 | p. 22 | Concentrates
Issue Date: August 25, 2014

Hydrogel Drug Depots Refilled On The Fly

DNA targeting allows implanted drug delivery hydrogels to be replenished multiple times by injections
Department: Science & Technology
News Channels: Materials SCENE, Biological SCENE
Keywords: drug delivery, hydrogel, doxorubicin

Implanted drug delivery devices are usually no good after they’ve released their contents. But a noninvasive refilling method could extend their lifetime, according to David J. Mooney and coworkers at Harvard University. The researchers have shown they can replenish hydrogel-based drug delivery depots in mice multiple times via intravenous injections (Proc. Natl. Acad. Sci. USA 2014, DOI: 10.1073/pnas.1413027111). The drug-laden hydrogels are made of . . .

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