Volume 93 Issue 10 | p. 5 | News of The Week
Issue Date: March 9, 2015 | Web Date: March 6, 2015

Helping Brains Relieve Anxiety

Neuroscience: Phosphatase inhibitor restores regulatory circuit
Department: Science & Technology
News Channels: Biological SCENE
Keywords: disorders, amygdala, endocannabinoids, benzodiazepines, phosphatase inhibitors

A new study suggests a strategy to treat anxiety might be to design drugs that help the brain’s own regulatory circuitry kick in and tune down hyperactive neurons.

The study’s authors focus on a part of the brain that processes fear and other emotions—the amygdala. In anxious mice, the researchers found, this region of the brain plays host to an overactive enzyme that disrupts a regulatory signaling system responsible for preventing nerve cells from becoming . . .

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