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Teva Pays Big For Deuterium Specialist

by Rick Mullin
April 6, 2015 | A version of this story appeared in Volume 93, Issue 14

Teva Pharmaceuticals will acquire Auspex Pharmaceuticals, a specialist in applying deuterium chemistry, for $3.2 billion. La Jolla, Calif.-based Auspex substitutes deuterium for hydrogen in known molecules to create therapies with improved safety and efficacy. Its SD-809 (deutetrabenazine) drug candidatehas delivered positive Phase III clinical trial results as a treatment for Huntington’s disease with a pharmacokinetic profile that allows for lower doses. Auspex hopes to file a New Drug Application this year. SD-809 is also being developed to treat tardive dyskinesia and Tourette’s syndrome.

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