Volume 93 Issue 19 | p. 26 | Concentrates
Issue Date: May 11, 2015

Metabolomics Reveals Vicious Cancer-Biofilm Cycle

Cell Metabolism: Colon cancer stimulates growth of cancer-promoting bacterial biofilms that in turn stoke cancer cells
Department: Science & Technology
Keywords: metabolomics, bacteria, biofilms, colon cancer

Researchers have proposed that bacterial biofilms might play a role in colon cancer, but experimental verification for the proposal has been sparse. A new study of the phenomenon now reveals a vicious cancer-biofilm cycle: Colon cancer stimulates further growth of bacterial biofilms in the colon, and the biofilms promote further proliferation of the cancer (Cell Metab. 2015, DOI: 10.1016/j.cmet.2015.04.011). The findings show that antibiotic treatment of bacteria eliminates biofilms and therefore might impede . . .

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