Volume 93 Issue 38 | p. 7 | News of The Week
Issue Date: September 28, 2015 | Web Date: September 24, 2015

Chemical Modification Is Best Ever At Strengthening And Stabilizing Collagen

Biomaterials: Changing glycine to aza-glycine in the protein’s backbone enhances hydrogen bonding, improving the material’s properties
Department: Science & Technology | Collection: Life Sciences
News Channels: Materials SCENE, Biological SCENE
Keywords: collagen, amino acid, aza-glycine

By switching out a single amino acid, researchers have dramatically improved the strength and stability of collagen, the protein scaffold found in the bodies of people and animals. The advance could lead to new biomaterials for a range of applications.

Collagen, the most abundant protein in mammals, is found in tendons, ligaments, cartilage, bones, blood vessels, skin, and other tissues. In the 1950s, legendary scientific figures such as chemist Linus Pauling, physicist G. N. Ramachandran, . . .

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