Volume 93 Issue 8 | p. 39
Issue Date: February 23, 2015

Life Science Researchers Call For Antibody Standardization

All antibody reagents should be sequenced and then produced using those sequences in a standardized way, scientists say
Department: Science & Technology
News Channels: Biological SCENE
Keywords: reproducibility, antibodies, reagents

Reproducibility remains a problem in life sciences research. A major cause of the lingering issue is poorly characterized reagents—especially antibodies—that can vary wildly in composition and yield different results in different labs.

A group of scientists has issued a call for the community to improve the quality of antibodies and other protein-binding reagents. In a comment in Nature, Andrew Bradbury of Los Alamos National Laboratory, Andreas Plückthun of the University of Zurich, . . .

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