Volume 94 Issue 3 | p. 8 | News of The Week
Issue Date: January 18, 2016 | Web Date: January 14, 2016

Fixing Iron Levels In Lung Cells Could Treat COPD

Drug Development: Study shows that concentrations of the metal inside cell organelles increase in mice with the disease
Department: Science & Technology
News Channels: Biological SCENE
Keywords: chronic obstructive pulmonary disease, COPD, lungs, iron, chelation

Patients with chronic obstructive pulmonary disease (COPD)—a group of disorders that include chronic bronchitis and emphysema—struggle to breathe and rely on drugs called bronchodilators to widen their obstructed airways. But these drugs just relieve symptoms of COPD and don’t stop the underlying mechanisms that cause this progressive disease.

A new study reports a possible COPD mechanism in which iron levels in the mitochondria of lung cells are elevated, damaging the critical cellular powerhouses. A small . . .

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