Volume 94 Issue 47 | p. 13 | News of The Week
Issue Date: November 28, 2016 | Web Date: November 23, 2016

Lilly Alzheimer’s drug fails

The firm will not seek regulatory approval for solanezumab
Department: Business
Keywords: drug development, solanezumab, Eli Lilly, Alzheimer’s disease

In yet another blow to the amyloid hypothesis, Eli Lilly & Co. said today that its Alzheimer’s treatment solanezumab failed in a Phase III study. Shares of Lilly were down as much as 15% on the news.

For more than a decade, Alzheimer’s drug developers have focused their efforts on trying to prevent or remove the amyloid plaques coating the brains of people with the disease. Solanezumab, which binds to soluble, monomeric forms of amyloid-β, . . .

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