Issue Date: February 1, 2016
Iron Catalysts For Enantioselective Hydrogenations
Making chiral alcohols and amines via enantioselective hydrogenation of ketones and imines is a cinch for chemists. But the ruthenium, iridium, and rhodium catalysts usually used for such transformations are expensive and toxic, which makes them unattractive for industrial applications. Because many pharmaceuticals, agrochemicals, flavors, and fragrances feature alcohols or amines with a stereogenic carbon at the α-position, chemists have been developing inexpensive, nontoxic iron catalysts capable of doing the same reaction. Until now, however, . . .
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- Chemical & Engineering News
- ISSN 0009-2347
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