Volume 94 Issue 6 | p. 23 | Concentrates
Issue Date: February 8, 2016

Probing Diversity-Generating Metabolic Pathways

Natural Products: In pathways that produce many different compounds, each step is slower than the ones before
Department: Science & Technology
News Channels: Biological SCENE
Keywords: natural products, diversity, reaction pathway, metabolism

Unlike conventional metabolic pathways that lead to a single product, diversity-generating pathways produce many compounds. Understanding such diversity-generating pathways could help researchers develop combinatorial biosynthetic pathways. A team of researchers led by Baldomero M. Olivera and Eric W. Schmidt of the University of Utah shows how one such pathway from cyanobacteria differs significantly from conventional metabolic pathways. The researchers focused on the tru pathway, which synthesizes a diverse family . . .

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