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Web Date: August 10, 2016

Radiotracer helps neuroscientists study epigenetics in the brain

Molecule maps density of histone deacetylases in people
Department: Science & Technology
News Channels: Analytical SCENE, Biological SCENE
Keywords: neuroscience, imaging, PET, epigenetics, histone deacetylase

Cells deploy an arsenal of enzymes to chemically modify DNA and its protein packaging. These so-called epigenetic modifications regulate the expression of genes, tuning the function of individual cells.

Neuroscientists have found that, in neurons, this enzymatic arsenal plays a significant role in learning and memory. And data suggest that dysfunction of epigenetic machinery is linked to neurological and psychiatric disorders, such as Alzheimer’s disease, schizophrenia, and depression.

Now a team of researchers at Massachusetts . . .

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Chemical & Engineering News
ISSN 0009-2347
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