Fluorinated azides click to make triazoles | Chemical & Engineering News
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Web Date: December 13, 2016

Fluorinated azides click to make triazoles

Researchers create new reagents for a fluorinated version of copper-catalyzed azide-alkyne click chemistry
Department: Science & Technology
Keywords: reagents, click chemistry, azide, fluorination

With the help of new fluorinating reagents, a team led by Zsófia E. Blastik and Petr Beier of the Czech Academy of Sciences has devised a versatile fluorinated version of copper-catalyzed click chemistry. The approach overcomes some previous difficulties with preparing suitable fluorinated reagents for click reactions and opens the door to broader use of click chemistry, which has become invaluable to biochemistry and polymer science researchers.

The new chemistry hinges . . .

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