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Web Date: December 12, 2016

New technique shocks proteins into action

Electric fields spark internal motions that can be observed, showing how proteins do their jobs
Department: Science & Technology
News Channels: Analytical SCENE, Biological SCENE
Keywords: structural biology, electric pulses, electric fields, X-ray crystallography, proteins, conformations

For a protein to carry out its job—whether it be replicating DNA, metabolizing fuel, transporting biomolecules, or sending cell signals—its amino acids have to move in certain ways. The patterns of these internal motions aren’t always well understood because the tools available to study them are limited.

A new technique, electric field-stimulated X-ray crystallography (EF-X), combines electric pulses with time-resolved X-ray crystallography to provide more comprehensive views of the ways proteins work. Electrical charges and . . .

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Chemical & Engineering News
ISSN 0009-2347
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