Volume 95 Issue 2 | p. 6 | News of The Week
Issue Date: January 9, 2017 | Web Date: January 4, 2017

Probing fibrils from different types of Alzheimer’s

Differences in fibril structure may correlate with different forms of the disease
Department: Science & Technology
News Channels: Biological SCENE, Analytical SCENE
Keywords: structural biology, Alzheimer’s disease, amyloid fibrils

A hallmark of Alzheimer’s disease is the accumulation of amyloid-β fibrils in the brain. It’s still an open question whether structural differences in these fibrils correlate with different subtypes of the disease such as so-called rapid-progression Alzheimer’s.

To help answer that question, Robert Tycko and coworkers at the National Institutes of Health have used brain tissue from patients with one of three forms of Alzheimer’s disease to seed the formation of fibrils . . .

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ISSN 0009-2347
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