Issue Date: July 24, 2017
Two new ways to get proteins into cells
Proteins can be important therapeutics, but in many cases their potential is limited because their polarity and large size prevent them from traversing cell membranes and entering cells, where their molecular targets may be located. Cell-penetrating peptides can shepherd proteins into cells, but in many cases the proteins are taken up by and retained in cell endosomes and thus still don’t reach the cytosol, the aqueous component of the cytoplasm. Two groups have now devised . . .
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- Chemical & Engineering News
- ISSN 0009-2347
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