Issue Date: August 7, 2017 | Web Date: August 2, 2017
CRISPR corrects mutation in human embryos
For the first time in the U.S., researchers have used the CRISPR-Cas9 gene-editing system in human embryos to correct a harmful hereditary gene mutation.
Led by Shoukhrat Mitalipov of Oregon Health & Science University, the team injected eggs from healthy donors with sperm from a donor with hypertrophic cardiomyopathy, a common condition characterized by irregular heartbeat and heart failure. People with the disease carry a mutation in one of two copies of . . .
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