Volume 95 Issue 47 | p. 6 | News of The Week
Issue Date: November 27, 2017 | Web Date: November 20, 2017

New possible target for rapid antidepressants found

Navitor molecule boosts mTORC1 activity, reduces depression symptoms in rats
Department: Science & Technology
Keywords: Drug discovery, rapid antidepressant, mTORC1 activation

People with depression have to take currently available antidepressants for months before they start to get relief from their symptoms. But scientists are on the hunt for new, fast-acting antidepressants.

For example, ketamine can improve symptoms in a matter of hours, but comes with some undesirable side effects, such as hallucinations and out-of-body experiences. So researchers want to understand which cellular pathways ketamine turns on and off to find possible new antidepressant drug targets that . . .

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Chemical & Engineering News
ISSN 0009-2347
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