Volume 96 Issue 10 | pp. 15-18
Issue Date: March 5, 2018

As the triple quadrupole turns 40, mass spec gurus look back on what it’s meant to chemistry

Mass analyzer remains popular for quantitative applications that require sensitivity and selectivity
Department: Science & Technology
Keywords: Mass spectrometry, analytical chemistry, instrumentation, history

Christie G. Enke and Richard A. Yost didn’t set out to make a mass spectrometer. Their goal was to completely computerize an analytical instrument. It was 1975, still the early days of teaming up manually operated instruments with computers.

Enke and Yost’s report of the triple quadrupole mass spectrometer in the Journal of the American Chemical Society on March 29, 1978 (DOI: 10.1021/ja00475a072), is often . . .

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