Issue Date: February 26, 2018 | Web Date: February 22, 2018
Aryl C–H bonds succumb to fluorination
A general and mild method for turning aromatic C–H bonds into C–F bonds offers chemists a way to create fluorinated molecules that were difficult to make before. Because the chemistry tolerates a broad range of functional groups, it can fluorinate molecules in the later stages of a chemical synthesis—to make novel pharmaceutical or agrochemical candidates, for example (Nature 2018, DOI: 10.1038/nature25749).
Chemists have already come up with good ways . . .
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