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Neuroscience

Celgene buys into Prothena programs

by Lisa M. Jarvis
March 26, 2018 | A version of this story appeared in Volume 96, Issue 13
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Celgene will pay Prothena $100 million up front as part of a pact to develop antibodies against three neuroscience drug targets: tau, a protein linked to Alzheimer’s disease; TDP-43, a protein implicated in amyotrophic lateral sclerosis; and an undisclosed target. The deal, which also calls for Celgene to take an equity stake in Prothena worth $50 million, comes at a time when Celgene is trying to bolster its neurodegenerative disease pipeline. Celgene can license the U.S. rights to drug candidates after Phase I studies.

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