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GSK will pay 4-year-old start-up Rgenta Therapeutics up to $46 million in up-front cash and preoption milestone payments—with the potential for up to $500 million in additional milestone payments—to develop small-molecule splice modulators for cancers and other diseases. Rgenta’s molecules are designed to stop RNA from encoding proteins that cause diseases. The firm launched in 2020 with $20 million in seed funding and raised $52 million in a series A round in 2022.
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