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Investment

Takeda partners with StrideBio to make new AAVs for neurological diseases

by Ryan Cross
April 12, 2019 | A version of this story appeared in Volume 97, Issue 15
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Takeda Pharmaceutical has picked the gene-therapy start-up StrideBio to make new adeno-associated viruses (AAVs) for delivering DNA into the central nervous system. The duo will work on therapies for Friedreich’s ataxia and two undisclosed conditions. StrideBio designs AAVs that evade takedown by the preexisting immune response some people have to AAVs. The start-up’s viruses are also designed for delivery to specific cell types. Takeda will pay StrideBio about $30 million up front and potentially $680 million more in the future.

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