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Outsourcing

Sterling to make API in flow process

by Michael McCoy
October 13, 2024 | A version of this story appeared in Volume 102, Issue 32
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A close-up of a flow chemistry reactor.
Credit: Sterling Pharma Solutions
A close-up of the flow reactor build by Peschl Ultraviolet

The pharmaceutical services provider Sterling Pharma Solutions will produce hypericin, the active ingredient in an oncology drug being developed by the biotech firm Soligenix. Sterling says it will conduct the synthesis at its plant in Germantown, Wisconsin. The synthesis will include a photocatalyzed intramolecular cyclization reaction that takes place in a flow reactor built by the German firm Peschl Ultraviolet. Hypericin is applied as an ointment to cutaneous T-cell lymphoma lesions and then activated by fluorescent light.

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