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Start-ups

Arrakis raises $75 million series B for RNA-targeting small molecules

by Ryan Cross
April 20, 2019 | A version of this story appeared in Volume 97, Issue 16
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Arrakis Therapeutics has raised $75 million in series B financing to advance its pipeline of small-molecule drugs that target RNA. The start-up has spent the past 2 years building a platform to screen compound libraries against RNA molecules that encode proteins considered undruggable. One of those proteins is a cancer-connected transcription factor called Myc. Arrakis has found molecules that may be able to prevent transcription of Myc messenger RNA, thereby lowering levels of the protein.

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