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Start-ups

Boehringer Ingelheim licenses bacteriophage-derived lysin therapies from Bioharmony

by Ryan Cross
January 18, 2019 | A version of this story appeared in Volume 97, Issue 3
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Boehringer Ingelheim is taking a new approach to fighting antibiotic-resistant bacteria. The German drug giant has struck a licensing and research agreement with the New York City–based start-up Bioharmony Therapeutics to develop therapies out of lysins, enzymes made by the bacteria-killing viruses called bacteriophages. Bioharmony hopes its lysins, based on work by microbiologist Vincent A. Fischetti at Rockefeller University, can tackle multidrug-resistant Gram-negative bacteria, which are considered some of the toughest to kill.

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