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Start-ups

Microbiome start-up Kaleido to shut down

by Michael McCoy
April 16, 2022 | A version of this story appeared in Volume 100, Issue 13
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Kaleido Biosciences, which was developing small-molecule compounds to modulate the human microbiome, has decided to shut down. The Lexington, Massachusetts–based firm was founded quietly in 2015 and emerged in 2017 with $65 million in funding. It went public in 2019 and at the end of 2021 had 76 employees. But Kaleido disclosed in January that it had halted work on a drug in Phase 2 studies for chronic obstructive pulmonary disease and ended an agreement with the COPD Foundation.

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