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Environment
Enabling Time-Of-Flight Mass Spec
December 9, 2013
| A version of this story appeared in
Volume 91, Issue 49
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“Mass Spec’s Century of Change” mentions the invention of time-of-flight (TOF) mass spectrometry by William E. Stephens (C&EN, Oct. 21, page 30). Two important breakthroughs that made this technique possible in practice also warrant mention: improvements in spatial and hence temporal resolution by W. C. Wiley and I. H. McLaren, scientists who worked at Bendix Corp. Wiley was also the inventor of the channel electron multiplier, which provided sufficiently short detector pulses to allow accurate timing of the arrival of ions and hence yield high-resolution mass spectrometry.
One could make the argument that Wiley was the father of modern TOF mass spectrometry.
J. Brian A. Mitchell
Rennes
France
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