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Science Communication

Fascinating findings of 2024

For their importance or wow factor, these advances snagged C&EN editors’ attention

by Prachi Patel
December 17, 2024 | A version of this story appeared in Volume 102, Issue 39

 

Electric attraction

When two people meet, some chemistry and a “spark” between them often leads to a deep connection. The same is apparently true for some metals and foods. Chemists found that applying an electric current at the interface between certain metals and various meats, vegetables, and fruits creates bonds that glue together the hard and soft materials (ACS Cent. Sci. 2024, DOI: 10.1021/acscentsci.3c01593). They remained stuck when the researchers turned the current off. Reversing the polarity of the current broke the bonds.

Listening to proteins fold

Sound helps us visualize things we cannot see. Scientists applied this principle to get a unique glimpse into the process of protein folding, which is key to understanding biological function. The researchers assigned a pitch to each hydrogen bond that forms during a simulation of a protein folding into a complex 3D structure. The simulation revealed the various routes—some slower than others—that proteins take on their folding journeys (Proc. Natl. Acad. Sci. U.S.A. 2024, DOI: 10.1073/pnas.2319094121).

Chemicals in plastic food packaging

Plastics contain chemicals. But just how many, and can they harm health? To find out, researchers collected plastic food packaging from five countries and used mass spectrometry to analyze chemicals extracted from the items (Environ. Sci. Technol. 2024, DOI: 10.1021/acs.est.3c08250). One piece of cling film from the UK contained a whopping 9,000-plus compounds. In laboratory tests on cells, extracts from all the samples interacted with cell receptors that play key roles in human endocrine and metabolic systems.

Lasers liberate hydrogen

When made by splitting water using renewable electricity, hydrogen is a valuable green fuel. But it is expensive and tricky to transport. Some companies want to use ammonia as a hydrogen carrier. Releasing that hydrogen typically requires heat, pressure, or catalysts. This year, researchers showed that you could instead zap ammonia-water solutions with brief, intense laser pulses to free the hydrogen (J. Am. Chem. Soc. 2024, DOI: 10.1021/jacs.3c13459). Using solar-pumped lasers for this process would make it energy efficient.

Quartz + quakes = gold

Quartz’s piezoelectricity—its ability to generate voltage under mechanical strain—is the secret behind the formation of gold nuggets in quartz deposits near geological fault zones (Nat. Geosci. 2024, DOI: 10.1038/s41561-024-01514-1). Researchers confirmed this idea by submerging quartz in gold-containing solution and applying strain to simulate a quake. The quartz develops cracks that fill with gold-laced water. It also produces voltage, and the electrons reduce gold ions in the water, thus precipitating solid gold.

Disorder gives blue hues

Many birds and bugs have vibrant colors not because of pigments and colorful compounds but because of the way tiny structures on their bodies reflect light. In this world of so-called structural color, order is usually key. Blue fruits bend that rule, researchers discovered this year. They examined blueberries, plums, and other blue fruits with a scanning electron microscope and found that the fruits’ distinct hue, in fact, arises from the disordered structure of their waxy outer coating (Sci. Adv. 2024, DOI: 10.1126/sciadv.adk4219).

Cryptic brain preservation

Brains usually dissolve within days after death. Depending on environmental conditions, though, five processes can preserve brains for hundreds or even thousands of years, researchers concluded after analyzing records of over 4,400 brain fossils (Proc. R. Soc. B 2024, DOI: 10.1098/rspb.2023.2606). Freezing, tanning, dehydrating, and saponifying all do the trick. A fifth, cryptic, method preserved brains for as long as 12,000 years. The team’s theory is that, catalyzed by iron, proteins and lipids in the brain cross-link to form stable molecules.

Body battery

Our bodies are chock-full of reactive chemicals and ions. Why not use them to power medical implants and wearables? That was the thinking of researchers who created a metal-oxygen battery that uses the body’s oxygen as a continuous energy source (Chem 2024, DOI: 10.1016/j.chempr.2024.02.012). The proof-of-concept device uses a sodium-based anode and a nanoporous gold cathode. But in the future, this type of battery could use sodium ions found in the body.

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Fascinating findings of 2024

Electric attraction

A clump of raw chicken and a tomato hang from a small, flat graphite electrode as if stuck. A curly piece of a red onion also hangs from an electrode from one end, and it has another electrode stuck to its other end.
An applied current makes a piece of chicken and a tomato stick to an anode, while an onion sticks to both an anode and a cathode.
Credit: Wenhao Xu and Srinivasa Raghavan/University of Maryland, College Park
A clump of raw chicken and a tomato hang from a small, flat graphite electrode as if stuck. A curly piece of a red onion also hangs from an electrode from one end, and it has another electrode stuck to its other end.
An applied current makes a piece of chicken and a tomato stick to an anode, while an onion sticks to both an anode and a cathode.
Credit: Wenhao Xu and Srinivasa Raghavan/University of Maryland, College Park

When two people meet, some chemistry and a "spark" between them often leads to a deep connection. The same is apparently true for some metals and foods. Chemists found that applying an electric current at the interface between certain metals and various meats, vegetables, and fruits creates bonds that glue together the hard and soft materials (ACS Cent. Sci. 2024, DOI: 10.1021/acscentsci.3c01593). They remained stuck when the researchers turned the current off. Reversing the polarity of the current broke the bonds.

Listening to proteins fold

Curly, windy structure of deoxyhemoglobin that uses different-colors to represent protein chains.
New research turns data into sound as a way to improve scientists' understanding of the process of protein folding.
Credit: Shutterstock
Curly, windy structure of deoxyhemoglobin that uses different-colors to represent protein chains.
New research turns data into sound as a way to improve scientists' understanding of the process of protein folding.
Credit: Shutterstock

Sound helps us visualize things we cannot see. Scientists applied this principle to get a unique glimpse into the process of protein folding, which is key to understanding biological function. The researchers assigned a pitch to each hydrogen bond that forms during a simulation of a protein folding into a complex 3D structure. The simulation revealed the various routes—some slower than others—that proteins take on their folding journeys (Proc. Natl. Acad. Sci. U.S.A. 2024, DOI: 10.1073/pnas.2319094121).

Chemicals in plastic food packaging

Several clear colorless plastic containers food containers, including some clamshell take-out containers and egg containers cartons.
A study examining plastic food packaging from five countries found that most items contained endocrine- and metabolism-disrupting chemicals.
Credit: Shutterstock
Several clear colorless plastic containers food containers, including some clamshell take-out containers and egg containers cartons.
A study examining plastic food packaging from five countries found that most items contained endocrine- and metabolism-disrupting chemicals.
Credit: Shutterstock

Plastics contain chemicals. But just how many, and can they harm health? To find out, researchers collected plastic food packaging from five countries and used mass spectrometry to analyze chemicals extracted from the items (Environ. Sci. Technol. 2024, DOI: 10.1021/acs.est.3c08250). One piece of cling film from the UK contained a whopping 9,000-plus compounds. In laboratory tests on cells, extracts from all the samples interacted with cell receptors that play key roles in human endocrine and metabolic systems.

Lasers liberate hydrogen

A schematic shows a laser pulse focused on a small point in an ammonia-water solution and creating a small spot of high energy plasma.
Laser pulses can form a bubble of plasma in an ammonia-water solution and create hydrogen gas.
Credit: Will Ludwig/C&EN/Adapted from J. Am. Chem. Soc.
A schematic shows a laser pulse focused on a small point in an ammonia-water solution and creating a small spot of high energy plasma.
Laser pulses can form a bubble of plasma in an ammonia-water solution and create hydrogen gas.
Credit: Will Ludwig/C&EN/Adapted from J. Am. Chem. Soc.

When made by splitting water using renewable electricity, hydrogen is a valuable green fuel. But it is expensive and tricky to transport. Some companies want to use ammonia as a hydrogen carrier. Releasing that hydrogen typically requires heat, pressure, or catalysts. This year, researchers showed that you could instead zap ammonia-water solutions with brief, intense laser pulses to free the hydrogen (J. Am. Chem. Soc. 2024, DOI: 10.1021/jacs.3c13459). Using solar-pumped lasers for this process would make it energy efficient.

Quartz + quakes = gold

Gold is embedded in opaque quartz.
Gold is embedded in opaque quartz.
Credit: Shutterstock
Gold is embedded in opaque quartz.
Gold is embedded in opaque quartz.
Credit: Shutterstock

Quartz's piezoelectricity—its ability to generate voltage under mechanical strain—is the secret behind the formation of gold nuggets in quartz deposits near geological fault zones (Nat. Geosci. 2024, DOI: 10.1038/s41561-024-01514-1). Researchers confirmed this idea by submerging quartz in gold-containing solution and applying strain to simulate a quake. The quartz develops cracks that fill with gold-laced water. It also produces voltage, and the electrons reduce gold ions in the water, thus precipitating solid gold.

Disorder gives blue hues

The blue fruits of Mahonia aquifolium.
The distinctive blue fruits of Mahonia aquifolium or the Oregon grape
Credit: Rox Middleton
The blue fruits of Mahonia aquifolium.
The distinctive blue fruits of Mahonia aquifolium or the Oregon grape
Credit: Rox Middleton

Many birds and bugs have vibrant colors not because of pigments and colorful compounds but because of the way tiny structures on their bodies reflect light. In this world of so-called structural color, order is usually key. Blue fruits bend that rule, researchers discovered this year. They examined blueberries, plums, and other blue fruits with a scanning electron microscope and found that the fruits' distinct hue, in fact, arises from the disordered structure of their waxy outer coating (Sci. Adv. 2024, DOI: 10.1126/sciadv.adk4219).

Cryptic brain preservation

A scientist holds a brain in a dish.
Forensic anthropologist Alexandra Morton-Hayward holds a 2,000-year-old brain. Such brains may be more prevalent in the fossil record than researchers have realized.
Credit: Graham Poulter
A scientist holds a brain in a dish.
Forensic anthropologist Alexandra Morton-Hayward holds a 2,000-year-old brain. Such brains may be more prevalent in the fossil record than researchers have realized.
Credit: Graham Poulter

Brains usually dissolve within days after death. Depending on environmental conditions, though, five processes can preserve brains for hundreds or even thousands of years, researchers concluded after analyzing records of over 4,400 brain fossils (Proc. R. Soc. B 2024, DOI: 10.1098/rspb.2023.2606). Freezing, tanning, dehydrating, and saponifying all do the trick. A fifth, cryptic, method preserved brains for as long as 12,000 years. The team's theory is that, catalyzed by iron, proteins and lipids in the brain cross-link to form stable molecules.

Body battery

On the left, a schematic of a battery with oxygen bubbles at one electrode; on the right is an image of a thin battery pouch.
A soft, flexible implantable battery made of a sodium-gallium-tin alloy anode and a nanoporous gold cathode is packaged in a porous polymer that allows oxygen from the body's fluids to fuel electricity-producing reactions.
Credit: Chem
On the left, a schematic of a battery with oxygen bubbles at one electrode; on the right is an image of a thin battery pouch.
A soft, flexible implantable battery made of a sodium-gallium-tin alloy anode and a nanoporous gold cathode is packaged in a porous polymer that allows oxygen from the body's fluids to fuel electricity-producing reactions.
Credit: Chem

Our bodies are chock-full of reactive chemicals and ions. Why not use them to power medical implants and wearables? That was the thinking of researchers who created a metal-oxygen battery that uses the body's oxygen as a continuous energy source (Chem 2024, DOI: 10.1016/j.chempr.2024.02.012). The proof-of-concept device uses a sodium-based anode and a nanoporous gold cathode. But in the future, this type of battery could use sodium ions found in the body.

A clump of raw chicken and a tomato hang from a small, flat graphite electrode as if stuck. A curly piece of a red onion also hangs from an electrode from one end, and it has another electrode stuck to its other end.
An applied current makes a piece of chicken and a tomato stick to an anode, while an onion sticks to both an anode and a cathode.
Credit: Wenhao Xu and Srinivasa Raghavan/University of Maryland, College Park
Curly, windy structure of deoxyhemoglobin that uses different-colors to represent protein chains.
New research turns data into sound as a way to improve scientists' understanding of the process of protein folding.
Credit: Shutterstock
Several clear colorless plastic containers food containers, including some clamshell take-out containers and egg containers cartons.
A study examining plastic food packaging from five countries found that most items contained endocrine- and metabolism-disrupting chemicals.
Credit: Shutterstock
A schematic shows a laser pulse focused on a small point in an ammonia-water solution and creating a small spot of high energy plasma.
Laser pulses can form a bubble of plasma in an ammonia-water solution and create hydrogen gas.
Credit: Will Ludwig/C&EN/Adapted from J. Am. Chem. Soc.
Gold is embedded in opaque quartz.
Gold is embedded in opaque quartz.
Credit: Shutterstock
The blue fruits of Mahonia aquifolium.
The distinctive blue fruits of Mahonia aquifolium or the Oregon grape
Credit: Rox Middleton
A scientist holds a brain in a dish.
Forensic anthropologist Alexandra Morton-Hayward holds a 2,000-year-old brain. Such brains may be more prevalent in the fossil record than researchers have realized.
Credit: Graham Poulter
On the left, a schematic of a battery with oxygen bubbles at one electrode; on the right is an image of a thin battery pouch.
A soft, flexible implantable battery made of a sodium-gallium-tin alloy anode and a nanoporous gold cathode is packaged in a porous polymer that allows oxygen from the body's fluids to fuel electricity-producing reactions.
Credit: Chem

 

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