The Importance of Radioligand Receptor Binding Assays for Drug Discovery and Development | C&EN Webinars | Chemical & Engineering News
The Importance of Radioligand Receptor Binding
Assays for Drug Discovery and Development

Live Webinar: October 28, 2010
11:00 a.m. EDT • 8:00 a.m. PDT • 5:00 p.m. CET (Europe)

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Overview: Radioligands enable academic and industry researchers to directly study the biochemical and functional binding responses of a wide range of cellular receptor sites at the molecular level, without the variables associated with non-radiometric methods. Today, with more than 300 NEN® radioligands available, scientists are able to identify, characterize and manipulate ligand-receptor interactions, while still employing radiometric detection as the gold standard of measurement for the discovery and development of drugs in today’s pharmaceutical market.

This webinar will examine the following:
  • Unique properties and characteristics of radioligands
  • Radioligand Binding Assay applications and feasibility
  • Methods for use of reference radioligands in primary screening, profiling, affinity and kinetics

Points to learn from the webinar:
  • The ability to accelerate the pace and clinical relevance of drug discovery research
  • The use of radioligands to achieve hit identification, lead optimization, and liability studies
  • Radiometric Detection as a simple and flexible assay using biologically equivalent radioligands
  • Selection of platforms (membranes/microplates/SPA beads) and instrumentation

Main Speaker:
Rajendrani (Raj) Mukhopadhyay, Ph.D.
Freelance Science Writer and Editor



Host for this Webinar:
Jeffrey Killian, Ph.D. Director, Bio-discovery Global Technical Support
PerkinElmer, Inc.



Featured Speakers:
Scott Perschke, M.S. Director, Assay Development Caliper Discovery Alliances and Services (formerly NovaScreen Biosciences)



Martha Widra Manager/Contract Manager, Environmental Health & Safety Coordinator Coordinator, Immunology Caliper Discovery Alliances and Services (formerly NovaScreen Biosciences)


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