CEN Webinars: Stronger Bonds
Modern Open Access Analytical Systems:
Truly Automated Purification
Thursday April 10th 2014
8:00 a.m. PDT / 11:00 a.m. EDT / 15:00 GMT
SPEAKERS
Speaker
Smriti Khera, Ph.D.
Pharmaceutical Discovery
Marketing Manager
Agilent Technologies, Inc.
Santa Clara, USA
 
Speaker
Andreas Tei, Ph.D.
Preparative HPLC
Product Manager
Agilent Technologies, Inc.
Waldbronn, Germany
 
Speaker
Fabrizio Giordanetto, Ph.D.
Director Medicinal Chemistry
Taros Chemicals GmbH & Co.
Dortmund, Germany
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OVERVIEW

Purification of target compounds is a critical analytical challenge during chemical matter generation faced by all synthetic organic chemists. Specifically, pharmaceutical chemists in the discovery stage require purifying many, sometimes libraries, of compounds for evaluating biological activities and any potential toxicity of discovery compounds. A successful purification involves several labor intensive analytical and preparative method development steps, and is traditionally performed by experts in a centralized purification laboratory. Past attempts to automate this critical application have not been amenable to use in open access.

In this seminar, we will introduce a truly automated purification system and software which can for the first time overcome the challenges a non-expert faces in going from analysis to purification and can thus reduce the workloads of purification experts by making purification successfully implementable in open access.

WHO SHOULD ATTEND

- Pharmaceutical medicinal and process chemists

- All organic chemists who utilize purification

- Chemistry lab managers, project leaders, or managers making purchase decisions for Chemistry in Biotech, Pharmaceutical companies, CRO's, academia, other chemical industries

- Open access administrators or Analytical chemists overseeing open access or walk-up instrumentation

- Analytical chemists supporting synthetic organic chemists

KEY LEARNING OBJECTIVES
  • • Potential benefits of using an automated purification
  •  
  • • Complete automated workflow from reaction confirmation to method development to purification
  •  
  • • How it all works
  •  
  • • Purifying samples in a high throughput environment
SPONSOR
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MODERATOR
Speaker
Ann Thayer
Senior Correspondent,
C&EN