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Enhance Your Chromatographic Separations with Superficially Porous Particles



  March 28, 2019

  8:00 a.m. PDT / 11:00 a.m. EDT / 15:00 GMT / 16:00 CET




An ongoing effort to modernize USP methods for HPLC analysis is in progress. There are criteria in effect which allow changes in column without having to revalidate the method. For those running legacy HPLC methods, switching to superficially porous particle columns offers several advantages including reduced analysis time/higher throughput, increased efficiency, and improved resolution.

In this webcast, we will highlight case studies that compare existing methods using fully porous particle columns to separations using superficially porous particle columns. When developing new methods, the choice of which stationary phase to select can also be challenging. Using a strategy to screen several different stationary phases when developing methods can be more effective than just starting with a C18 column. The second part of this webcast will show example comparisons across various stationary phases. Whether an analyst is looking to improve an existing method or developing a new method, employing superficially porous particle columns will enable fast, efficient separations.

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Key Learning Objectives

  • Understand the advantages of superficially porous particles compared to fully porous particles for pharmaceutical separations
  • Learn how to modernize USP methods for HPLC by changing from a fully porous particle column to a superficially porous particle column
  • Review examples that demonstrate the advantages of having a variety of stationary phases for method development

Who Should Attend

  • Method developers for UHPLC/UPLC and HPLC methods in pharmaceutical, chemical, clinical, environmental, agrichemical, university and governmental laboratories
  • LC Chromatographers looking to modernize USP methods


Stephanie A. Schuster, Ph.D.,
Application and Quality Manager,
Advanced Materials Technology, Inc.


Patricia Daukantas,
Contributing Editor,
C&EN BrandLab