Determination of HAAs in Drinking Water Matrices with IC-MS/MS and 2D-IC
CEN Webinars: Stronger Bonds

C&EN Webinar Series — Advanced IC Applications for Compliance Monitoring in Drinking Water

Part 3: Determination of HAAs in
Drinking Water Matrices with IC-MS/MS and 2D-IC


Thursday, May 23, 2013

USA 11:00 a.m. EDT / 10:00 a.m. CDT / 8:00 a.m. PDT / 16:00 BST


Who should attend?

• Water utility operators interested in analysis of disinfection byproducts for compliance monitoring

• Scientists interested in the latest developments in analytical methods

• Lab managers who are considering new IC instrumentation for these applications


Bryan M. Hill, Sr.
Lead Sanitary Chemist, Organics/Inorganic Division
Erie County Public Health Laboratory

Richard F. Jack,
NA Market Manager, Environmental
Thermo Fisher Scientific Inc.


Celia Henry Arnaud
Senior Editor

Register for the other parts of this series, and view more webinars sponsored by Thermo Scientific by clicking here.


Haloacetic acids (HAAs) are among the disinfection byproducts produced during chlorination of water which contains natural organic matter and bromide. Some of the approved methods for compliance monitoring—including U.S. EPA Methods 552.1, 552.2, 552.3 and Standard Method 6251B—are fairly challenging and time consuming, as each requires extraction and derivatization. Ion chromatography-mass spectrometry (IC-MS/MS), per EPA Method 557 promulgated in December 2009, offers a sensitive and selective alternative that does not require sample pretreatment. Excellent peak resolution and linearity are achieved for analyte concentrations between 0.4 and 100 μg/L in a high fortified matrix. The detection limit is less than 0.4 μg/L for each of the five regulated HAAs and less than 1 μg/L for the other four. Using the spike recoveries of all nine HAAs' variability between methods ranged from 70 to 130% for most determinations.

We will also explore the use of two-dimensional IC (2D-IC) for HAA analysis. This strategy builds on existing 2D methods approved in EPA Methods 302 and 314.2 for bromate and perchlorate, respectively. When combined with capillary IC, detection limits of sub ppb are achieved from direct injection of drinking water samples.

Key Learning Objectives:

• The latest IC-MS/MS technique for HAAs per EPA Method 557.

• Recent developments in analysis of HAAs for process optimization and compliance monitoring.

• New methods in HAA analysis using 2D-IC and 2D-capillary IC.

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