Solving the Structures of Parkinson's Biomarkers with Integrative Mass Spectrometry Tools
November 29, 2017
8:00 a.m. PST / 11:00 a.m. EST / 16:00 GMT / 17:00 CET
Proteins are central to cellular function, playing crucial roles in nearly every biological process that occurs within a cell, from gene expression to cell growth and proliferation, intercellular communication and apoptosis. Understanding the intricate structures of these proteins, protein complexes and their interactions are key to finding innovative ways to intervene in disease processes and find new preventative measures, treatments, and pharmaceutical agents.
Advances in biomolecular mass spectrometry (MS) have had a significant impact on the field of structural biology. Technology developments in mass analyzers are the driving force behind the growing number of structural biology studies that have led to a plethora of MS methods, particularly at the intact protein and peptide levels, which allow the characterization of biomolecular structures.
Brought to you by:
• Learn about mass spectrometry techniques such as hydrogen-deuterium exchange HDX-MS, cross-linking XL-MS and UVPD used in structural proteomics
• Application of integrated workflows that accelerate the path from structure to function
• Researchers interested in Structural Proteomics
• Core Laboratory Scientists
• Researchers performing disease-related studies
Christoph Borchers, Ph.D.,
Professor, University of Victoria Director,
UVic Genome BC Proteomics Centre