Automated Characterization of Proteins, Polymers and
Nanoparticles with Dynamic Light Scattering

Thursday, September 15, 2011
USA: 11:00 a.m. EDT • 10:00 a.m. CDT • 8:00 a.m. PDT
Europe: 5:00 p.m. Berlin • 4:00 p.m. London

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Overview: In this webinar we will introduce and review the analytical technique of dynamic light scattering (DLS), discuss what can and cannot be measured using DLS, and discuss the throughput capability and sample requirements of the method. A number of applications will be discussed including measurements of nanoparticles, formulation and stability, molecular/particle association/ disassociation values, protein melting/ aggregation temperatures, and critical micelle concentrations.

What you'll learn in this webinar:
  • How liquid-borne samples can be analyzed without perturbation in a matter of seconds using DLS to obtain size and size distributions.
  • How rapid, automated sequences can be set up for unattended data acquisition and analysis.
  • What DLS can (and cannot) measure.
  • How DLS may be used to measure sizes and size distributions of nanoparticles and molecules.
  • How to determine association and disassociation values of protein-protein complexes, and discover inhibitors of association.
  • Information which may be obtained from concentration or temperature dependent studies (e.g. critical micelle concentration, or protein melting temperature).
  • How to accomplish rapid and miniaturized assessment of second virial coefficients.

Who should attend?
  • Any scientist interested in characterizing particle, size, shape and density of sub-micron-sized samples in solution.
  • Researchers who want to learn about a state-ofthe- art analytical technique for rapidly characterizing proteins, particles and polymers in solution.
  • Scientists involved with modifying proteins, polymers or nanoparticles who want rapid feedback on those modifications.

Speakers:
Michael LarkinMichael Larkin, Ph.D.
Principal Scientist
Wyatt Technology Corporation




Moderator:
Elizabeth K. WilsonElizabeth K. Wilson
Senior Editor,
C&EN



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