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Absolute Molar Mass Analysis of Medical Device and Pharmaceutical Polymers
June 18, 2019
8:00 a.m. PDT,
11:00 a.m. EDT,
16:00 BST, 17:00 CEST
Polymers used in medical devices and drug-delivery systems, as active pharmaceutical ingredients, and especially bio-absorbables, invariably require reliable characterization of the molar mass distribution. The types of polymers used in these applications can be difficult to analyze using size exclusion chromatography (SEC) due to limited solubility, interactions with column packings, or high molar mass.
This webinar will provide insight into the methods used for absolute molar mass analysis of modern medical polymers, primarily multi-angle light scattering measurements coupled to size-exclusion chromatography (SEC-MALS). Case studies will be presented to illustrate some of the techniques employed to solve the analytical challenges these materials present.
The unique challenges involved with the analysis of therapeutic polypeptides, resorbable polyesters, and hyaluronic acid will be discussed. Though the theme of the presented case studies is specific, the techniques outlined are applicable to a broad range of SEC analyses.